Can Spurs end that barren run?
We all know Harry Kane has hit the ground running in his first two full England caps. This time we’ll see if he can finally convert his impressive performances into Premier League goals.
The 23-year-old hit double figures for the first time in all competitions at Wembley two years ago, but has failed to find the net in 15 league games since.
Only against Arsenal last season, when Kane inspired the first win of Mauricio Pochettino’s tenure, did he manage to score for Spurs.
Gareth Southgate will be hoping his striker can finally show his world-class talent in a Spurs shirt this season.
Our team of Premier League experts pick their tips for the first few fixtures.
Our team of pundits: Caelainn Nicholson and Robert Crawford (BBC Radio 5 live), Gary Lineker (BBC Radio 5 live), Martin Keown (BBC Radio 5 live), Alan Hansen (BBC Sport), John Arlott (BBC Sport), Alan Shearer (BBC Sport), Alan Smith (BBC Radio 5 live), Shane Warne (Guinness World Records), Mark Noble (Arsenal) and Sam Burgess (Leeds United).